复旦大学中山医院程韵枫教授在CMI发文，MST4通过磷酸化STAT1介导巨噬细胞M1极化促进ITP

原发性免疫性血小板减少症 (ITP) 是一种获得性自身免疫性出血性疾病，其中自身抗体调理的血小板在脾和/或肝脏中被巨噬细胞过早清除。巨噬细胞在先天性和适应性免疫反应中发挥多种作用，可以根据环境刺激极化为经典激活的 M1 巨噬细胞或选择性激活的 M2 巨噬细胞。在 ITP 患者的脾脏和外周血中观察到 M1 巨噬细胞大量扩增，其可以通过 Fcγ 受体 (FcγR) 吞...

Generalized Varying Coefficient Mediation Models

Motivated by an analysis of causal mechanism from economic stress to entrepreneurial withdrawals through depressed affect, we develop a two-layer generalized varying coefficient mediation model. This model captures the bridging effects of mediators that may vary with another variable, by treating them as smooth functions of this variable. It also allows various response types by introducing the ge...

Electron Affinities in the Periodic Table and an Example for As

Based on our previous analysis of electron affinities of atoms and structures of atomic negative ions [J. Phys. Chem. Ref. Data 51, 021502 (2022)], this review provides a concise presentation of the electron affinities of atoms. We briefly describe and compare three commonly used experimental methods for determining electron affinities to highlight their respective advantages and disadvantage...

A novel CBAMs-BiLSTM model for Chinese stock market forecasting

The convolutional block attention module (CBAM) has demonstrated its superiority in various prediction problems, as it effectively enhances the prediction accuracy of deep learning models. However, there has been limited research testing the effectiveness of CBAM in predicting stock indexes. To address this gap and improve the prediction accuracy of stock indexes, we propose a novel model called C...